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FDA-Approved REMS-Certified Clinic Most Insurance Accepted Frederick, MD

SPRAVATO® (Esketamine) Nasal Spray in Frederick, MD

FDA-approved SPRAVATO® (esketamine) nasal spray for treatment-resistant depression. Most insurance accepted. Free consultation with our care team, under the guidance of a Johns Hopkins-trained psychiatrist.

  • Free 30-minute confidential consultation
  • Free insurance verification — no obligation to commit
  • Johns Hopkins-trained psychiatrist, REMS-certified clinic
~70% Response Rate
+52% Remission Odds
4.8★ Patient Rating

Based on pooled analysis of TRANSFORM-1 & TRANSFORM-2 Phase 3 trials. Popova V, et al. J Affect Disord. 2023.

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30 minutes · No cost · No obligation

HIPAA Compliant REMS Certified 4.8★ Patient Rating

Is SPRAVATO® Right for You?

Most patients who benefit from SPRAVATO® share these things in common. If most of these apply to you, you may be a strong candidate for treatment.

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You may be a strong candidate if…

  • You're an adult, age 18 or older
  • You've tried two or more antidepressants without lasting relief
  • You've been diagnosed with major depressive disorder
  • You can travel to our Frederick, MD clinic for in-person sessions
  • You're ready to explore an FDA-approved alternative to standard antidepressants

We Accept Most Major Insurance Plans

SPRAVATO® is typically covered by these providers. We'll verify your specific plan for free before you commit to treatment.

SPRAVATO® Works Differently Than Antidepressants

Unlike traditional antidepressants that target serotonin and can take 4–8 weeks to work, SPRAVATO® targets a different system in the brain — and many patients experience relief in days, not months.

Traditional Antidepressants

SSRIs / SNRIs

  • Target serotonin & norepinephrine
  • 4–8 weeks to show full effect
  • May not work for treatment-resistant cases
  • Must be taken daily, indefinitely
SPRAVATO® (Esketamine)

FDA-Approved Option

  • Targets glutamate — a different system
  • Relief possible within days, not months
  • FDA-approved for treatment-resistant depression
  • In-clinic sessions, supervised by a physician

Targets a Different System

SPRAVATO® works on glutamate, the brain's main excitatory neurotransmitter. Traditional antidepressants target serotonin. This is why SPRAVATO® may work when SSRIs and SNRIs have not.

Rapid Relief in Days, Not Months

Many patients report improvement within the first one to two weeks. Traditional antidepressants typically take four to eight weeks — if they work at all.

Administered Under Medical Supervision

Self-administered as a nasal spray during in-clinic sessions at our REMS-certified Frederick, MD location. You stay for monitoring after each dose to ensure safety.

Here's What to Expect, From First Call to Recovery

A straightforward path designed to feel calm and supported — not clinical and confusing. Each step builds on the last.

  1. Free Consultation · 30 minutes · Phone

    Free Consultation

    A no-cost call with our team to confirm you're a candidate, answer your questions, and verify your insurance coverage at no charge. No commitment required.

  2. Psychiatric Evaluation · 60 minutes · In-person

    Psychiatric Evaluation

    A thorough evaluation with our Johns Hopkins-trained psychiatrist to confirm diagnosis, review your treatment history, and build a personalized plan.

  3. Treatment Sessions · 2 hours · In-clinic

    Treatment Sessions

    Self-administer the nasal spray in a quiet, private room at our Frederick, MD clinic. Stay for two hours of monitoring while our team supports you. Please arrange a ride home — no driving the same day.

  4. Ongoing Monitoring · Long-term care

    Ongoing Monitoring

    Track your progress with standardized rating scales at every visit. Adjust your plan as needed. We coordinate with your therapist or primary care doctor as appropriate.

Ready to start? It begins with a free, no-obligation phone call.

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Dr. Amir Etesam, MD — Founder and Lead Psychiatrist at Bright Horizons Psychiatry Johns Hopkins-Affiliated

Amir Etesam, MD

Founder & Lead Psychiatrist, Bright Horizons Psychiatry

  • Johns Hopkins Training

    Completed Psychiatry Residency at Johns Hopkins University — one of the world's top-ranked psychiatry programs — with a focus on mood disorders and advanced treatments.

  • Board-Certified Psychiatrist

    American Board of Psychiatry and Neurology certified.

  • Specialty Focus

    Treatment-resistant depression, SPRAVATO®, Deep TMS, IM ketamine, and complex mood disorders in adults.

  • REMS-Certified for SPRAVATO®

    Bright Horizons is a Risk Evaluation and Mitigation Strategy (REMS) certified clinic, meeting FDA requirements for safe esketamine administration.

"Most patients who come to me have tried everything. My job is to take that seriously, look at what hasn't worked and why, and offer treatments that actually fit the science of what's happening in their brain. People deserve more than another prescription."
— Dr. Amir Etesam, MD

NPI: 1588144588 · License: Maryland

Your Questions, Answered

Everything you need to know before your free consultation. Don't see your question? Call us or ask during your call.

Is SPRAVATO® covered by insurance?

Yes. SPRAVATO® is FDA-approved and typically covered by most major insurance plans, including Aetna, Blue Cross Blue Shield, Cigna, Tricare, United Healthcare, Maryland Medicaid, and Medicare.

Coverage usually requires prior authorization. We handle the entire prior authorization process for you at no cost. We'll also verify your specific plan and any out-of-pocket costs during your free consultation so you know exactly what to expect.

What are the side effects of SPRAVATO®?

The most common side effects during the two-hour monitoring period are temporary and typically resolve before you leave the clinic. They include:

  • Dissociation (a brief, mild feeling of being detached from your surroundings)
  • Dizziness or sedation
  • Increased blood pressure
  • Nausea
  • Mild headache

Because of these effects, you must be monitored on-site for two hours after each dose and cannot drive for the rest of the day. Our clinical team monitors your blood pressure, comfort, and safety throughout. Serious side effects are rare and the medication is administered under FDA REMS-certified safety protocols.

How long does it take for SPRAVATO® to work?

Many patients begin to notice improvement within the first one to two weeks of treatment — in contrast to traditional antidepressants, which typically take four to eight weeks.

The standard course is twice-weekly sessions for the first four weeks (induction phase), followed by less frequent maintenance sessions. Response is monitored at every visit using standardized rating scales. Results vary by patient — some respond quickly; others need the full induction phase. Your psychiatrist will set expectations during your initial evaluation.

What happens during a SPRAVATO® session?

Each session lasts approximately two hours at our Frederick, MD clinic (7360 Guilford Dr STE 100) in a quiet, private treatment room. Here's what to expect:

  • Check-in & vitals: Brief check-in, blood pressure reading, review of how you're feeling
  • Self-administration: You'll self-administer the SPRAVATO® nasal spray under supervision
  • Monitoring: Two hours of relaxed monitoring in a calm, comfortable space
  • Discharge: Once your vitals are stable, you'll be cleared to leave with arranged transportation
Can I drive home after a SPRAVATO® session?

No. FDA REMS safety protocols require that you do not drive, operate machinery, or perform any activity requiring full alertness for the remainder of the day after each SPRAVATO® session.

You must arrange transportation home from each visit — a family member or friend, rideshare (Uber or Lyft), or a taxi. The next day, you can typically return to normal activities, including driving, unless your psychiatrist advises otherwise.

How do I get started?

Getting started is straightforward and risk-free:

  • Step 1: Book your free 30-minute consultation using the form above or by calling (240) 599-1001
  • Step 2: We'll verify your insurance coverage and any out-of-pocket costs at no charge
  • Step 3: If you qualify and want to move forward, we'll schedule your in-person evaluation
  • Step 4: Once approved, you can typically start treatment within one to two weeks

The free consultation has no cost and no obligation — it's simply a conversation to see if SPRAVATO® is right for you.

Still have questions? That's exactly what your free consultation is for.

Book My Free Consultation

30 minutes · No cost · No obligation

Now Accepting New Patients in Frederick, MD

When You're Ready, We're Here

You've tried enough things that didn't work. SPRAVATO® might be different — and the only way to know is a 30-minute conversation with our team.

30 Minutes Completely Free No Obligation
FDA-Approved REMS-Certified Clinic Johns Hopkins-Trained Frederick, MD